Volume 15, Issue 46 (12-2014)                   Zanko J Med Sci 2014, 15(46): 59-65 | Back to browse issues page

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Farahani F, Permeh P, Nasiri S, Gohari Kakhaki A R, Mohamad Gharachik B, Sohrabipoor J. Biological properties of Brown algae in Northern Coast of Persian Gulf. Zanko J Med Sci 2014; 15 (46) :59-65
URL: http://zanko.muk.ac.ir/article-1-29-en.html
Abstract:   (4644 Views)
Abstract
Background and Aim: The widespread use of antibiotics leads to resistant strains of microorganisms and antibiotic resistance is increasing throughout the world, therefore, access to new sources of drugs with fewer side effects is important. This paper examines the effects of biological extracts of ethylacetate, methanol and methanol-water of Colpomenia sinousa and Iyengaria stellata in the Northern coast of the Persian Gulf. 
Methods: In this study after sampling, antibacterial effects of extracts of Colpomenia sinousa and Iyengaria stellata collected from Persian Gulf on a strain of bacteria called Staphylococcus aureus(gram-positive) and E.coli (gram-negative), Pseudomonas aeruginosa examined and the results were compared with standard antibiotics. Extraction was performed using percolation method. Antibacterial effects (MIC) of the extracts were determined. 
Results: Results of the dilution tests showed, the algal extracts had antibacterial effect and among the extracts, ethyl acetate extracts of Iyengaria stellata (MIC> 2/5 mg / ml) compared to the positive control against three strains of bacteria, have the greatest effect (p <0/05). 
Conclusion: All three extracts, ethyl acetate, methanol and methanol-water of Colpomenia sinousa and Iyengaria stellata Showed antibacterial effects of Persian Gulf Coast, ethyl acetate extract of Iyengaria stellata greatest effect on each of the three strains of bacteria Staphylococcus aureus (PTCC: 1112), E coli (PTCC: 1338), Pseudomonas aeruginosa (PTCC1707) and showed that there was significant difference with the positive control (p <0.05).
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Type of Study: Research | Subject: Special
Received: 2014/10/5 | Accepted: 2014/11/19 | ePublished: 2014/12/6

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