Background and Aim: The prevalence of cancer in different parts has different patterns. Knowing frequency of malignancies in different age groups, the primary component of prevention programs at different levels is. Breast cancer is the second leading cause of cancer deaths in women. This study aimed to investigate the prevalence of breast cancer in Kermanshah has been ten years.

Materials and Methods: The study was a retrospective historical cohort. The data were extracted from health Center cancer registry of Kermanshah province during 2004 to 2013. Data analysis was performed using the software SPSS18.

Results: The results of this study showed that during the ten -year statistics of 1976 people have been diagnosed with breast cancer, The most frequent breast cancer and 260 (%13.16) is in 1392. Among women aged 40-49 years, and among women aged 40-49 years have the highest risk of this cancer.

Conclusion: Ten -year statistics shows the increase in the incidence of breast cancer in Kermanshah had cancer.  According to the cancer registry system has better performance than in the past, but likelihood of increasingly frequent due to changing lifestyles and increased breast cancer risk factors also clearly be seen. With planning for primary prevention can be do effective measures to reduce or diagnose the disease at an early stage.