RT - Journal Article T1 - The effect of colloidal silver nanoparticles on histopathology of zebra fish (Danio rerio) gill JF - muk-zanko YR - 2014 JO - muk-zanko VO - 15 IS - 45 UR - http://zanko.muk.ac.ir/article-1-31-en.html SP - 1 EP - 8 K1 - Histopathology K1 - hypertrophy K1 - necrosis K1 - silver nanoparticles K1 - zebra Fish AB - Abstract Background and Aim: Nowadays, due to the wide applications of silver nanoparticles increased them into the environment. In this context, the arrival of these nanomaterials to the environment has the potential to impact on living organisms, including fish. Therefore, the purpose of this study was the effect of silver nanoparticles on gill histological of zebra fish (Danio rerio).Methods: In this study, three non-lethal concentrations of silver nanoparticles were used that included 0.25, 0.1, and 0.05 mg/l also control group was considered. For studies of classic histological, the samples were prepared and stained by haematoxylin - eosin, and finally was imagined by light microscopy. Results: Histopathological studies of gill tissue showed that the silver nanoparticles on gill tissue cause some impact such as secondary bending blades, blades secondary hypertrophy, increased mucus secretion, fusion in the secondary lamellae, hyperplasia and eventually necrosis increases. Although histological changes in gill tissue were observed in all groups, but the severity of these changes increased with increasing concentration of silver nanoparticles.Conclusion: Due to changes in zebra fish gill tissue at different concentrations of silver nanoparticles in comparison with the control group, such as hyperplasia, hypertrophy, and ultimately necrosis, it can be said that silver nanoparticles can have considerable effects on fish gill tissue. Pathology studies can be simple and convenient tool to assess the impact of environmental pollutants on fish used. LA eng UL http://zanko.muk.ac.ir/article-1-31-en.html M3 ER -