%0 Journal Article %A Amin Menbari, Armaghan %A Setayeshfar, Masoomeh %A Akhdar, Sako %A Nouri, Bijan %A Menabri, Shaho %T Antibiotic Resistance Pattern in Uropathogenic Escherichia coli Phylogenetic Groups Isolated from Hospitals of Sanandaj in 2017 %J Zanko Journal of Medical Sciences %V 19 %N 62 %U http://zanko.muk.ac.ir/article-1-394-en.html %R %D 2018 %K Uropathogenic E. coli, Antibiotic resistance pattern, Phylogenetic group, %X Background and Aim: Escherichia coli is the most common cause of urinary tract infections. This pathogen is divided into 8 phylogenetic groups: A, B1, B2, C, D, E, F, and clade I. The study of phylogenetic groups and their antibiotic resistance in different geographic regions is necessary in order to obtain epidemiological information and better treatment. Material and Method: In this study, 119 strains of E. coli which were obtained from patients with urinary tract infection were subjected to phylogenetic typing by a quadruplex-PCR method. Antimicrobial susceptibility testing was also performed by agar diffusion test. Results: The prevalence of phylogenetic groups in E. coli isolates was B2 (47.9%), C (10.9%), D (9.2%), A (8.4%), F (7.6%), E (5.9%), B1 (5%), Clade I (3.4%), and Unknown (1.7%). The highest resistance rates were observed for ampicillin (80.6%) and cotrimoxazole (66.4%). The most effective antibiotics were imipenem (100%) and nitrofurantoin (92%). There was no significant correlation between antibiotic resistance and phylogenetic groups. Conclusion: Group B2 was the most phylogenetic group which poses highest resistant to various antibiotics among patients with urinary tract infections. To treat more effectively and prevent the emergence of resistant strains, an antibiotic susceptibility test is essential before treating urinary tract infections caused by Escherichia coli. %> http://zanko.muk.ac.ir/article-1-394-en.pdf %P 31-41 %& 31 %! %9 Research %L A-10-52-1 %+ Kurdistan University of Medical Sciences %G eng %@ 2383-3343 %[ 2018