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Background: Depression is known as one of the four important diseases and the most prevalent disability as a result of disease across the world. Various medical students who are involved with maintaining mental and physical health of society are more vulnerable to this disorder due to their special position. The aim of this study was to investigate the prevalence of depression among medical students of Jahrom University of Medical Sciences in 2013-2014. Methods and Materials: This study was a cross-sectional study and was conducted on 360 university students at Jahrom University of Medical Sciences in 2013. Data were obtained by Beck Depression Test and were analyzed by SPSS software version 15. Results: Results associated with the prevalence of depression in medical students based on the severity indicated that 47 students (13.1%) had moderate depression and 32 students (18.9%) had severe depression. Fisher's exact test did not indicate any significant statistical differences with regard to family history and depression (P = 0.21). Discussion and Conclusion: Considering the results of the present study, there is a necessity to adopt policies to reduce the factors contributing to the incidence of depression and its consequences would be prevented by a quick and timely diagnosis.

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